Protective cardiovascular and renal actions of vitamin D and estrogen
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چکیده
منابع مشابه
Protective cardiovascular and renal actions of vitamin D and estrogen.
Both basic science and clinical studies support the concept that vitamin D deficiency is involved in the pathogenesis of cardiovascular and renal diseases through its association with diabetes, obesity, and hypertension. Understanding the underlying mechanisms may provide a rationale for advocating adequate intake of vitamin D and calcium in all populations, thereby preventing many chronic dise...
متن کاملRenal actions of vitamin D in D-deficient rats.
COSTANZO, LINDA S., PAUL R. SHEEHE, AND Il. M. WEINER. Renal actions uf uitamin D in D-dqkient rats. Am. J . Ph ysiol. 226 (6) : 1490-1495. 1974.-The renal clearances of calcium and phosphate were studied in vitamin D-deficient rats and similar rats repleted with 100 U of vitamin D 48 h prior to the experiments. Thyroparathyroidectomy (T-PTX) was performed on all animals immediately before the ...
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The effects of vitamin D receptor activation on cardiovascular diseases, especially hypertension and cardiac dysfunction, are areas of active investigation. This article reviews the current state of knowledge about vitamin D receptor activation with respect to blood pressure, heart, and vascular health, as well as to chronic kidney disease and end-stage renal disease. Potential biological mecha...
متن کاملAutocrine and paracrine actions of vitamin d.
Vitamin D deficiency continues to attract considerable attention because of claims that an adequate status can reduce the risk of a wide range of diseases. The facts are that this hormone modulates the expression of a very large number of genes, possibly some 5 to 10% of the genome; that it has been subject to very strong evolutionary pressures; and that its biological activities are exerted ac...
متن کاملVitamin D and cardiovascular prevention.
Vitamin D has been known to medical science for almost a century. Yet, it is only in the last 15 years that we have realized that the biological effects of vitamin D extend far beyond the control of calcium metabolism. Recent observational evidence suggests strong links between low vitamin D levels and a range of cardiovascular conditions, including stroke, myocardial infarction, hypertension, ...
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ژورنال
عنوان ژورنال: Frontiers in Bioscience
سال: 2013
ISSN: 1945-0516,1945-0524
DOI: 10.2741/s362